In this position paper, we describe our vision of the future of machine-based programming through a categorical examination of three pillars of research. Those pillars are: \emph{(i)} intention, \emph{(ii)} invention, and \emph{(iii)} adaptation. Intention emphasizes advancements in the human-to-computer and computer-to-machine-learning interfaces. Invention emphasizes the creation or refinement of algorithms or core hardware and software building blocks through machine learning (ML). Adaptation emphasizes advances in the use of ML-based constructs to autonomously evolve software.